Books authored and co-authored by members of the Luisi Lab.
Pier Luigi Luisi, Russian translation of The systems view of life
Pier Luigi Luisi, Essays on Life Sciences, with Related Science Fiction Stories
Cambridge scholars, UK, 2020
This collection of essays highlights, in a new, critical fashion, some of the classic questions in life science. These include "what is life?"; "what is death?"; "what is consciousness?"; "why is life cellular?"; and "why are enzymes macromolecules?". It also explores whether evolution is pre-determined, whether science and spirituality can harmonize with each other, whether artificial intelligence is at odds with the human spirit, and whether, and to what extent, we are genetically determined. In this text, some of the main conceptual tools used to tackle life's many aspects are necessarily reviewed, such as the systems view of life, the notion of contingency, and the concept of autopoiesis. Each of the three chapters of the book contains a number of short science fiction stories which discuss aspects of the present-day development of artificial intelligence
Pier Luigi Luisi, The Emergence of Life: From Chemical Origins to Synthetic Biology (2nd Edition)
Cambridge Univ. Press, UK, 2016
Addressing the emergence of life from a systems biology perspective, this new edition has undergone extensive revision, reflecting changes in scientific understanding and evolution of thought on the question 'what is life?'. With an emphasis on the philosophical aspects of science, including the epistemic features of modern synthetic biology, and also providing an updated view of the autopoiesis/cognition theory, the book gives an exhaustive treatment of the biophysical properties of vesicles, seen as the beginning of the 'road map' to the minimal cell - a road map which will develop into the question of whether and to what extent synthetic biology will be capable of making minimal life in the laboratory. Fully illustrated, accessibly written, directly challenging the reader with provocative questions, offering suggestions for research proposals, and including dialogues with contemporary authors such as Humberto Maturana, Albert Eschenmoser and Harold Morowitz, this is an ideal resource for researchers and students across fields including bioengineering, evolutionary biology, molecular biology, chemistry and chemical engineering.
The Danish translation of the book by Capra - Luisi “The systems view of life”
translation by Ole Lindgard Henriksen
Copenhagen, Latvia 2016
The Systems View of Life
Fritjof Capra and Pier Luigi Luisi , Cambridge Univ. Press, UK, 2014
Over the past thirty years, a new systemic conception of life has emerged at the forefront of science. New emphasis has been given to complexity, networks, and patterns of organisation, leading to a novel kind of 'systemic' thinking. This volume integrates the ideas, models, and theories underlying the systems view of life into a single coherent framework. Taking a broad sweep through history and across scientific disciplines, the authors examine the appearance of key concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systems view of life for health care, management, and our global ecological and economic crises are also discussed. Written primarily for undergraduates, it is also essential reading for graduate students and researchers interested in understanding the new systemic conception of life and its implications for a broad range of professions - from economics and politics to medicine, psychology and law.
Pier Luigi Luisi Tibetan translation of the book Mind and Life,
translated by Tenzin Rigsang, 2014
Vita e natura. Una visione sistemica
Negli ultimi trent'anni, nella scienza d'avanguardia, è emersa una nuova concezione sistemica della vita. Complessità, reti, network e pattern di organizzazione hanno ricevuto una rinnovata attenzione portando a un approccio innovativo, detto approccio "sistemico".
Pier Luigi Luis A Emergencia da Vida
Portughese translation of The emergence of life first ed.
Edit. Universidad Sao Paolo, Brazil, 2013
Pier Luigi Luisi Chinese translation of the book Chemical Synthetic Biology
China Science Publishing, 2013
Sull'origine della vita e della biodiversità
Pier Luigi Luisi , Mondadori, Milano, 2011
Il libro è una narrazione lunga oltre tre miliardi e mezzo di anni, dagli albori delle cellule primordiali fino alla ricchezza di forme e colori che caratterizza la nostra odierna biodiversità. È un lungo cammino ricco di dati scientifici, in cui vediamo la scoperta del codice genetico, la potenza della biotecnologia; un percorso costellato anche di domande pregnanti di sapore filosofico - l'origine della vita è stato un processo obbligato, o dovuto al caso? C'è un piano nella natura e nell'evoluzione biologica? Noi siamo davvero i nostri geni? È possibile costruire la vita in laboratorio? Fino ad arrivare alla fase finale del rapporto tra biodiversità e ecologia - perché ci sono venticinquemila specie di pesci diversi, e oltre quindicimila specie di farfalle diverse? E tutta questa biodiversità è destinata veramente a perire? Domande e aspetti tecnici cui il libro offre spunti di riflessione e ripensamento.
Chemical Synthetic Biology
Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.
Pier Luigi Luisi, Mind and Life: Discussions with the Dalai Lama on the Nature of Reality
Columbia univ. Press, 2011
For over a decade, members of the Mind and Life Institute have gathered to discuss questions that are both fundamental and profound: can physics, chemistry, and biology explain the mystery of life? How do our philosophical assumptions influence science and the ethics we bring to biotechnology? And how does an ancient spiritual tradition throw new light on these questions?
In Mind and Life, Pier Luigi Luisi reproduces this stimulating cross-cultural dialogue in which world-class scientists, philosophers, and Buddhist scholars develop a holistic approach to the exploration of reality. He also adds scientific background to their presentations, as well as supplementary discussions with prominent participants and attendees. Interviews with His Holiness the Karmapa, the Buddhist monk Matthieu Ricard, and the actor and longtime human rights advocate Richard Gere further enrich the material with personal viewpoints. Conversation topics range from the origin of matter to the nature of evolution, the ethics of genetic manipulation, and the question of consciousness and ethics.
Pier Luigi Luisi, La Vida Emergente
Spanish translation of the first edition of "The emergence of Life",
The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms.
Pier Luigi Luisi and Pasquale Stano, The Minimal Cell: The Biophysics of Cell Compartment and the Origin of Cell Functionality
Springer, Heidelberg 2010
In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands of molecules are organized spatially and functionally in order to realize what we call cellular life. This fact elicits the question whether such huge complexity is a necessary condition for life, or a simpler molecular system can also be defined as alive. Obviously, the concept of minimal cell encompasses entire families of cells, from totally synthetic cells, to semi-synthetic ones, to primitive cell models, to simple biomimetic cellular systems. Typically, in the experimental approach to the construction of minimal the main ingredient is the compartment. Lipid vesicles (liposomes) are used to host simple and complex molecular transformations, from single or multiple enzymic reactions, to polymerase chain reactions, to gene expression. Today this research is seen as part of the broader scenario of synthetic biology but it is rooted in origins of life studies, because the construction of a minimal cell might provide biophysical insights into the origins of primitive cells, and the emergence of life on earth. The volume provides an overview of physical, biochemical and functional studies on minimal cells, with emphasis to experimental approaches. 15 International experts report on their innovative contributions to the construction of minimal cells.
Pier Luigi Luisi Japanese translation of “The emergence of life”
First edition,Tuttle Mori Agency Tokyo 2006
The Emergence of Life: From Chemical Origins to Synthetic Biology
cambridge Univ. Press, first edition, UK, 2006
The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.
Pier Luigi Luisi and Peter Walde, Vom Ursprung des Universums zur Evolution des Geistes
vdf Hochschulverlag, Zurich, 2002
di Pier Luigi Luisi and Peter Walde, Giant Vesicles,
Wiley and Sons, N.Y., 1999
Perspectives in Supramolecular Chemistry Founded by J.-M. Lehn Perspectives in Supramolecular Chemistry reflects research which develops supramolecular structures with specific new properties, such as recognition, transport and simulation of biosystems or new materials. The series covers all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences reflecting the many and varied applications of supramolecular structures in modern chemistry. Giant Vesicles Edited by Pier Luigi Luisi and Peter Walde Institute f?r Polymere, ETH-Z?rich, Switzerland Giant vesicles or giant liposomes are supramolecular assembles of amphiphiles, surface active substances which normally contain one or two hydrophobic chains and one hydrophilic head. Due to their relatively large size, giant vesicles are easily observed by light microscopy. This volume provides an overview of ideas and results obtained from experimental studies as well as theoretical approaches. A wide variety of aspects ranging from pure mathematics and physical considerations to biochemical and biological applications are covered. Historical and fundamental aspects are discussed as well as a range of experimental approaches including the micromanipulation and micro-puncturing of single giant vesicles. 87 international contributors comment on a wide range of issues contained under the five main part headings: Introduction Preparation Methods Basic Theoretical Aspects Physical Properties Chemical and Biological Aspects. Giant Vesicles has been written for researchers in the fields of chemistry, biochemistry and biophysics, working in supra-molecular chemistry, surfactant science, liposome and pharmaceutical sciences.
Pier Luigi Luisi and Barbara E. Straub, Reverse Micelles: Biological and Technological Relevance of Amphiphilic Structures
Plenum Press, N.Y. and London, 1984