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Mercoledì, 10 Febbraio 2021 15:45

Utilizzo dei cookies

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Utilizzo dei cookies

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Mercoledì, 10 Febbraio 2021 15:43

Privacy policy

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Mercoledì, 21 Ottobre 2020 06:44

Curriculum vitæ

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Professor Emeritus at the ETHZ (Swiss Federal Institute of Technology)

Pier Luigi received his scientific education at the Scuola Normale Superiore in Pisa, Italy. In 1970, he became professor at the Institut für Polymere at the ETH-Zürich and since 2006 he is part of the biology department of the University of Roma Tre. As a biochemist, he pioneered an active research in the self-organization of synthetic and biological systems, the origin of life, and semi-synthetic cellular systems (the so-called "mininal life"). Interested in the interface between science and humanities, in 1985 he founded Cortona week, legacy to this Todi-week, and participated, in 1987, to the foundation of Mind and Life in Dharamsala, India, with Francisco Varela and the Dalai Lama.

 

1963 Laurea in chimica alla Scuola Normale Superiore di Pisa, magna cum laude.

1963 – 1969 Post-doc alla università di S. Petersburg, Russia, poi all’Università di Uppsala, Svezia, research fellow all’istituto di biologia molecolare in Eugene, Oregon.

1970 – 1982 Assistente al Politecnico Federale di Zurigo (all’ETH-Z), poi assistant professor, extraordinarius in chimica macromolecolare. Fondatore con il prof. Pino e prof. Meissner dell’Istituto dei Polimeri all’ETH-Z.

1984 Ordinario di chimica macromolecolare all’ETH-Zürich.

Dal 1985 organizzatore e direttore della settimana internazionale “Cortona-week”, ( scienza e la interezza della vita”) per l’integrazione tra le scienze naturali e umanistiche.

Dal 1987 al 2000 professore invitato alle Università di Nagasaki, Harvard, Saclay, Seoul, Osaka, San Diego.
1984 – 2002 chair per quattro volte dell’Istituto dei Polimeri all’ETH-Z

1991 Fondatore e presidente del Swiss Group Colloid Sceince.

1992 – 2000 chair di tre azioni cost “recognition chemistry”, “supramolecular chemistry”, “origin of life and early evolution”

Oct 96 – oct 98 chair of the department of chemistry at the ETH-Z

Settembre 2003 lascia l’ETH-Z con il titolo di Professore Emeritus

Novembre 2003 professore di biochimica alla Università di Roma3.

 

The various phases of the scientific activity of prof. PLL

for the paper numbers, see the list under papers; for the papers published monthly in WSI, see at the end of the same section. 

 

1. synthetic polymers, conformational studies.

The scientific activity begins with the thesis work at the Pisa University, under the direction of prof. Piero Pino, on isotactic vinyl polymers, with a thesis work carried out in (at that time) Leningrad, Soviet Union, in the group of prof. Volkenstein, under the direction of Dr. T. Birsthein. This work was continued in Pisa, with emphasis on optically active isotactic vinyl polymers and their low molecular weight compounds, also with interest in copolymers, as described in the first 11 papers. See also papers 14,16, 18, 20, 25,31, 49, 64, 77, 82, 88.

 

2. Enzymology and dehydrogenases

Following ca. 2 years of postdoc work in Eugene, Oregon, in the group of molecular biology of prof. Sidney Bernhard, there are work on alcohol dehydrogenase from horse liver, other enzymes and other dehydrogenases (in particular octopine dehydrogenases), carried out with stopped-flow techniques and fluorescence work, see papers 12,13, all the other till 32, (excluded the ones mentioned under 1) but see also 37, 40, 41,47, 48,49, 51,52, 53,54a, 56,57, 62, 87, 90, 93

 

3. Synthesis and spectroscopic properties of aromatic peptides.

work described in the papers 42-45,50, 61,65,66, 76, 79,80, 89,97

 

4. Proteases for the synthesis of peptide bonds, proteases in general, thioredoxin, protein folding

in papers 54,54a, 58,59, 68,69, 95,104, 107, 110, 115,118, 119, 128, 165, 174, 199,

 

5. micellar enzymology (and cell in reverse micelles)

see papers 55, 60, 63, 70, 71,72-75, 78, 86,96,98-103,105, 106, 108,109, 111-114,116,117,120-123, 125-127, 129, 132-129, 136, 139-146, 151, 154-156,158 a and b, 159-164, 167-168, 171, 172a, 175, 178, 179, 182, 186,187, 193,194, 196, 198, 208, 214, 216, 219, 222, 224,225, 288,318, 447

 

6. organogels

in papers 124, 130, 131, 159, 171, 173, 176, 180, 188, 204, 206, 210, 211, 220, 274, 280,282, 350

 

7. general reviews, philosophy, emergence, consciousness, AI,

67,83, 84,91, 92, 149, 177, 197, 201, 212, 252, 295, 298, 307, 316, 325, 326,327, 332-334, 347, 353, 354, 375, 386-388, 391, 442,467, 487, 517, 526, 529, 530, 532, 534,550b,

 

8. nucleic acids

see 85,96, 157, 214, 218, 267, 297, 300, 305, 309, 310, 339, 368, 373, 382, 398,408, 489, 537

 

9. autopoiesis, ool, chirality

170, 172, 180, 181, 184, 192, 231, 232, 245, 251, 253, 255, 273c, 275, 284, 295, 298, 338, 348, 355, 365, 370, 375, 379-381, 386, 394, 396, 405, 409-410, 414,424,a and b, 427,438,447,452,463,472, 478, 480, 484,485, 510, 519, 535,536,552,568,569, 571, 582

 

10. proteins in liposomes, liposomes, vesicles

166,183, 241,242, 243, 246, 248, 249, 267, 278, 283, 296, 304,305, 319, 325, 326, 328,329, 331-334, 336, 349, 351,352, 355-358, 377,378, 380, 386, 389,390, 395-397,399,401,402,406,407, 409-411, 413,431, 433, 449-451,458, 481-482, 598,

 

11. cubic phases

185, 215

 

12. giant vesicles

247, 259, 273b, 276, 311, 337, 339, 341-344, 346, 392, 528

 

13. minimal cell, synthetic biology

260, 267, 360, 374,379, 365, 374, 380,381, 400, 410, 422,424, 430, 433, 434, 448,450, 456,457,460,462,466,471,474,476b,473, 477,483, 488,489, 490-492,494-495, 498,499,501,502,504,505, 508, 511, 515,516,518, 522-525, 528, 538-541, 544,545,549,555,557,558,566, 578,586,587,

 

14. never born proteins

416-418, 420, 422, 423,426, 439,440, 503,504, 514

 

15, overcrowding 

493,500,513,550, 567, 570

---------------------------

Papers published monthly on Wall Street International (WSI):

this is the link to the papers in English: https://wsimag.com/authors/492-pier-luigi-luisi and this for the articles in italian: https://wsimag.com/it/authors/492-pier-luigi-luisi

Martedì, 21 Luglio 2020 13:39

Cortona Week

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“Science and the Wholeness of Life”

The concept

Cortona Week, a Summer School named after the small medieval town in Tuscany where it was initiated, has been for over 30 years an annual interdisciplinary week-long retreat providing a systemic, interdisciplinary view of the world, targeted to graduate students and young managers. Our aim is to foster a new generation of world leaders capable of tackling the ecological and ethical problems of our endangered planet. During the week, young (and not so young) students of various disciplines and nationalities mix with scientists, artists, philosophers, business leaders, and other professionals with the extraordinary possibility of building human relationships of a totally new kind in a process of transformative learning.

The venue place in Cortona, Tuscany, ItalyThe venue place in Cortona, Tuscany, Italy

The venue place in Cortona, Tuscany, Italy

 

The following paragraphs briefly describe the basic premise, history, faculty, and administration of the Cortona Week. For further information, please contact Prof. Pier Luigi Luisi, at    Questo indirizzo email è protetto dagli spambots. È necessario abilitare JavaScript per vederlo..

The premise

Our world leaders today generally come from our universities, which are able to produce good professionals but only in one discipline at a time. It is now rather obvious that the problems of our world — climate emergency, loss of biodiversity, energy crisis, economic inequality and mass migrations, just to mention a few — are systemic problems, which cannot be solved by one single discipline at a time. They need a systemic, interdisciplinary approach — exactly what the standard academic curriculum cannot offer. To address this dilemma, we offer an additional intensive, external summer course, organized as a retreat. The term “retreat” points to the fact that the focus is not primarily on transmitting data and information, but instead on radical transformative learning.

 

Our history

The Cortona Week was created in 1985 by Pier Luigi Luisi, at that time Professor of Macromolecular Chemistry at the Swiss Federal Institute of Technology, the famous ETH Zurich. It was designed as a Summer School for ETHZ students and was held annually after 1985. From the very beginning, Cortona Week was a great success with average participation of over 100 students and with enthusiastic support from eminent scientists, artists, and philosophers who joined the Summer School as speakers or workshop leaders.

During those years, Cortona Week was supported organizationally and financially by ETHZ.

When this support ended in 2017, a group of friends of Cortona thought that this was not the time in history to stop the formation of a new generation of leaders, and decided to create an Italian non-profit organization (Associazione di Promozione Sociale, or APS) with Prof. Luisi as the director, with the aim of continuing the Cortona Week. In 2018 and 2019, the continuing Summer School was held in the town of Todi in Umbria.

The meetings of 2018 and 2019 were again very successful. However, with the withdrawal of ETHZ two structural problems became apparent: the lack of academic support and financial problems. To sustain the costs of the week (mostly travel and accommodations of the presenters) it has been necessary to charge fees to the participants (1000 euros for students, 1500 euros for non-student; all included).

Picture 1 1

New venue and administration

After to years in Todi, the Cortona week is returning to its original place, Cortona, In Tuscany. See our web page for some information about this old famous Etruscan town (www.cortonafriends.org) under the directorship of  Prof. Luisi together with a team of young assistants. The Association’s Advisory Board is constituted of Michel Bitbol, Fritjof Capra, Kamrad Mofid, Renuka Singh, and Brother David Steindl-Rast.

The 2021 week will take place from June 26, Saturday, till July 3.th, Saturday at noon, at the Hotel Oasi Neuman, under the theme "Society in flux: choosing the paths". Registration on the afternoon of Friday, June 26.th.

Details on registration in our web page www.cortonafriends.org. In this page you will also find indications about traveling.

Here some more general information about the meeting/retreat.

Structure of the week

Cortona Week is now generally held during the last week of June. It begins with registration on Friday afternoon, and the working week goes from Saturday morning until lunch on the following Saturday, with a total of 7 full-board days and 8 nights. Partial participation is not allowed- in fact, the week is a kind of retreat. All meals and coffee breaks are spent together, and there is ample time and space for personal interactions.

Picture 1.3png  Picture 14

 

The working week has two main components: two main lectures in the morning and experiential workshops in the early morning (before breakfast) and in the afternoon. The lecturers are not only charismatic individuals who are specialists in their discipline, but are also capable of showing with the example of their lives that they stand behind their words.

Participants register for the workshops of their choice on the first day of the week. All workshops are optional and in parallel. Obviously, participants cannot follow all of them; they have to make choices. The early-morning workshops are devoted to meditation, yoga, Tai Ji, etc. The first session in the afternoon features workshops on theoretical subjects (ecology, literature, philosophy, etc.). The second session is dedicated to creative work (music, improvisational theater, painting, sculpture, etc.). The third session features more introspective, psychological work. The time after dinner is kept free on purpose, so as to facilitate personal encounters and discussions. Traditionally, however, there is an organ concert on the first Saturday night and a wonderful farewell party on the last night. For sample programs from 2018 and 2019, please see our website www.cortonafriends.org .

Faculty

It is not possible to mention all the speakers from the last 30 years or so. Here is a small selection from the past years:

Michel Bitbol                               Alexander Lowen

David Bohm                                Lynn Margulis

Fritjof Capra                                Hortense Reintjens

John Casti                                   Humberto Maturana

Luisa Damiano                             Tullio Regge

Richard Ernst                               Rupert Sheldrake

Federico Faggin                           Wolf Singer

Patricia Jennings                              Cliff Saron

Joan Halifax                                 Renuka Singh

Vittorio Gallese                            Br. David Steindl-Rast

Gioia Lussana                              William Irving Thompson

Albert Hoffmann                          Francisco Varela

Chungliang Al Huang                   Paul Watzlawick

Stuart Kauffman                           Anton Zeilinger

Alexander Laszlo                         Francisco Varela

Outreach

Over the past 30 years, each Cortona Week attracted about 120 participants, which means that over 3,000 people have been involved in it. However, this is still a small token with respect to what our world needs today. Our vision is to have not one, but 10, 100, 1000 Cortona Weeks in many colleges around the world. We are working on realizing this vision. So far, there have been two international Cortona weeks: one held in Hyderabad, India in 2010 (see www.cortona-india.org), and one for American Ph.D. students, sponsored by the Fetzer Institute, in 2009.

After the long affiliation with ETHZ, the Cortona Week has been without academic support and without a sponsor. The effort of the present organization is to overcome these two problems.

We are now contacting several universities in Italy and other European countries, as well as in the United States and Asia, asking them to include the Cortona week as a Summer School, or as a post-degree course, in their official curricula. In this way, their students would learn about Cortona Week and may apply. We would also like to ask these universities to possible finance the participation of some of their students (at the rate of 1000 euros per student). At the same time, we are developing our presence on social media to reach out to a potential global student body.

Lunedì, 20 Luglio 2020 10:08

Pier Luigi Luisi - Articles

Scritto da

 

The various phases of the scientific activity of prof. PLL

(not complete).

for the papers published monthly in WSI, see at the end of this.

 

1. synthetic polymers, conformational studies.

The scientific activity begins with the thesis work at the Pisa University, under the direction of prof. Piero Pino, on isotactic vinyl polymers, with a thesis work carried out in (at that time) Leningrad, Soviet Union, in the group of prof. Volkenstein, under the direction of Dr. T. Birsthein. This work was continued in Pisa, with emphasis on optically active isotactic vinyl polymers and their low molecular weight compounds, also with interest in copolymers, as described in the first 11 papers. See also papers 14,16, 18, 20, 25,31, 49, 64, 77, 82, 88.

 

2. Enzymology and dehydrogenases

Following ca. 2 years of postdoc work in Eugene, Oregon, in the group of molecular biology of prof. Sidney Bernhard, there are work on alcohol dehydrogenase from horse liver, other enzymes and other dehydrogenases (in particular octopine dehydrogenases), carried out with stopped-flow techniques and fluorescence work, see papers 12,13, all the other till 32, (excluded the ones mentioned under 1) but see also 37, 40, 41,47, 48,49, 51,52, 53,54a, 56,57, 62, 87, 90, 93

 

3. Synthesis and spectroscopic properties of aromatic peptides.

work described in the papers 42-45,50, 61,65,66, 76, 79,80, 89,97

 

4. Proteases for the synthesis of peptide bonds, proteases in general, thioredoxin, protein folding

in papers 54,54a, 58,59, 68,69, 95,104, 107, 110, 115,118, 119, 128, 165, 174, 199,

 

5. micellar enzymology (and cell in reverse micelles)

see papers 55, 60, 63, 70, 71,72-75, 78, 86,96,98-103,105, 106, 108,109, 111-114,116,117,120-123, 125-127, 129, 132-129, 136, 139-146, 151, 154-156,158 a and b, 159-164, 167-168, 171, 172a, 175, 178, 179, 182, 186,187, 193,194, 196, 198, 208, 214, 216, 219, 222, 224,225, 288,318, 447

 

 

6. organogels

in papers 124, 130, 131, 159, 171, 173, 176, 180, 188, 204, 206, 210, 211, 220, 274, 280,282, 350

 

7. general reviews, philosophy, emergence, consciousness, AI,

67,83, 84,91, 92, 149, 177, 197, 201, 212, 252, 295, 298, 307, 316, 325, 326,327, 332-334, 347, 353, 354, 375, 386-388, 391, 442,467, 487, 517, 526, 529, 530, 532, 534,550b,

 

8. nucleic acids

see 85,96, 157, 214, 218, 267, 297, 300, 305, 309, 310, 339, 368, 373, 382, 398,408, 489, 537

 

9. autopoiesis, ool, chirality

170, 172, 180, 181, 184, 192, 231, 232, 245, 251, 253, 255, 273c, 275, 284, 295, 298, 338, 348, 355, 365, 370, 375, 379-381, 386, 394, 396, 405, 409-410, 414,424,a and b, 427,438,447,452,463,472, 478, 480, 484,485, 510, 519, 535,536,552,568,569, 571, 582

 

10. proteins in liposomes, liposomes, vesicles

166,183, 241,242, 243, 246, 248, 249, 267, 278, 283, 296, 304,305, 319, 325, 326, 328,329, 331-334, 336, 349, 351,352, 355-358, 377,378, 380, 386, 389,390, 395-397,399,401,402,406,407, 409-411, 413,431, 433, 449-451,458, 481-482, 598,

 

11. cubic phases

185, 215

 

12. giant vesicles

247, 259, 273b, 276, 311, 337, 339, 341-344, 346, 392, 528

 

13. minimal cell, synthetic biology

260, 267, 360, 374,379, 365, 374, 380,381, 400, 410, 422,424, 430, 433, 434, 448,450, 456,457,460,462,466,471,474,476b,473, 477,483, 488,489, 490-492,494-495, 498,499,501,502,504,505, 508, 511, 515,516,518, 522-525, 528, 538-541, 544,545,549,555,557,558,566, 578,586,587,

 

 

14. never born proteins

416-418, 420, 422, 423,426, 439,440, 503,504, 514

 

15, overcrowding

 

493,500,513,550, 567, 570

 

 

---------------------------

papers published monthly on Wall Street International (WSI):

 

 

Lunedì, 20 Luglio 2020 08:32

Prof. Dr. Pier Luigi Luisi

Scritto da

 

Pier Luigi Luisi

Pier Luigi Luisi took a degree in Chemistry at the Scuola Normale Superiore of Pisa and held internships in the USA (Oregon, Institute of Molecular biology) and the Soviet Union (Leningrad, Institute of Macromolecular science).

From 1971 to 2003 his professional career was spent at the Swiss Federal Institute of Technology in Zürich. He became a full professor of Macromolecular Chemistry in the Department of Material Science, where he directed the Biopolymers section. He has been carrying research into the mechanism of enzymes, and the self-organization and self-reproduction of synthetic and natural systems.

Subsequently, he focused on the origins of life and, later, on synthetic biology, that of minimal cells in particular. Prof. Luisi, when working at the Swiss Federal Institute of Technology in Zurich, initiated in 1985 the Cortona-week, an interdisciplinary residential week in which graduate students were working together with artists, musicians, politicians, religious leaders, etc., with the aim of discovering new and broader horizons of life.

The latest books of prof Luisi are: "Essays on life science", Cambridge Scholars Publishing 2020; and “Le cinque porte della felicità” and “Il posto dei fichidindia” 2020.